3LE4

Crystal structure of the DGCR8 dimerization domain

Summary for 3LE4

Entry DOI	10.2210/pdb3le4/pdb
Descriptor	Microprocessor complex subunit DGCR8 (2 entities in total)
Functional Keywords	ww motif, dimerization, 3d domain swapping, heme binding, microrna processing, heme, iron, metal-binding, nucleus, phosphoprotein, rna-binding, nuclear protein
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q8WYQ5
Total number of polymer chains	1
Total formula weight	8888.26
Authors	Senturia, R.,Cascio, D.,Sawaya, M.,Guo, F. (deposition date: 2010-01-14, release date: 2010-07-07, Last modification date: 2024-02-21)
Primary citation	Senturia, R.,Faller, M.,Yin, S.,Loo, J.A.,Cascio, D.,Sawaya, M.R.,Hwang, D.,Clubb, R.T.,Guo, F. Structure of the dimerization domain of DiGeorge Critical Region 8 Protein Sci., 19:1354-1365, 2010 Cited by PubMed: 20506313 DOI: 10.1002/pro.414 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.701 Å)

Structure validation