3LCB

The crystal structure of isocitrate dehydrogenase kinase/phosphatase in complex with its substrate, isocitrate dehydrogenase, from Escherichia coli.

Summary for 3LCB

Entry DOI	10.2210/pdb3lcb/pdb
Related	3EPS 3LC6
Descriptor	Isocitrate dehydrogenase kinase/phosphatase, Isocitrate dehydrogenase [NADP], ADENOSINE MONOPHOSPHATE, ... (6 entities in total)
Functional Keywords	kinase phosphatase, glyoxylate bypass, hydrolaseprotein phosphatase, tricarboxylic acid cycle, isocitrate, transferase, hydrolase
Biological source	Escherichia coli More
Cellular location	Cytoplasm : B5Z0A8
Total number of polymer chains	4
Total formula weight	229023.65
Authors	Zheng, J.,Jia, Z. (deposition date: 2010-01-10, release date: 2010-04-21, Last modification date: 2024-02-21)
Primary citation	Zheng, J.,Jia, Z. Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase. Nature, 465:961-965, 2010 Cited by PubMed: 20505668 DOI: 10.1038/nature09088 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation