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3L2P

Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching Between Two DNA Bound States

Summary for 3L2P
Entry DOI10.2210/pdb3l2p/pdb
DescriptorDNA ligase 3, 5'-D(P*CP*GP*GP*GP*AP*TP*GP*CP*GP*TP*C)-3', 5'-D(*GP*TP*CP*GP*GP*AP*CP*TP*G)-3', ... (5 entities in total)
Functional Keywordsdna ligase, dna repair, atp-binding, cell cycle, cell division, dna damage, dna recombination, dna replication, ligase, magnesium, metal-binding, nucleotide-binding, nucleus, phosphoprotein, zinc-finger, ligase-dna complex, ligase/dna
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus: P49916
Total number of polymer chains4
Total formula weight78874.33
Authors
Cotner-Gohara, E.A.,Kim, I.K.,Hammel, M.,Tainer, J.A.,Tomkinson, A.,Ellenberger, T. (deposition date: 2009-12-15, release date: 2010-07-14, Last modification date: 2011-07-13)
Primary citationCotner-Gohara, E.,Kim, I.K.,Hammel, M.,Tainer, J.A.,Tomkinson, A.E.,Ellenberger, T.
Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching between Two DNA-Bound States.
Biochemistry, 49:6165-6176, 2010
Cited by
PubMed: 20518483
DOI: 10.1021/bi100503w
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

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