3L11

Crystal Structure of the Ring Domain of RNF168

Summary for 3L11

Entry DOI	10.2210/pdb3l11/pdb
Descriptor	E3 ubiquitin-protein ligase RNF168, ZINC ION, MALONATE ION, ... (4 entities in total)
Functional Keywords	e3 ligase, ring domain, dna damage, chromatin regulator, chromosomal protein, dna repair, ligase, metal-binding, nucleus, phosphoprotein, ubl conjugation pathway, zinc-finger, structural genomics, structural genomics consortium, sgc
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q8IYW5
Total number of polymer chains	1
Total formula weight	13466.16
Authors	Neculai, D.,Yermekbayeva, L.,Crombet, L.,Weigelt, J.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2009-12-10, release date: 2010-01-19, Last modification date: 2023-09-06)
Primary citation	Campbell, S.J.,Edwards, R.A.,Leung, C.C.,Neculai, D.,Hodge, C.D.,Dhe-Paganon, S.,Glover, J.N. Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation. J.Biol.Chem., 287:23900-23910, 2012 Cited by PubMed: 22589545 DOI: 10.1074/jbc.M112.359653 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.12 Å)

Structure validation