3KWY

Crystal structure of RXRalpha ligand binding domain in complex with triphenyltin and a coactivator fragment

Summary for 3KWY

Entry DOI	10.2210/pdb3kwy/pdb
Descriptor	Retinoic acid receptor RXR-alpha, Nuclear receptor coactivator 2 peptide, triphenylstannanyl, ... (5 entities in total)
Functional Keywords	nuclear receptor transcription organotin, dna-binding, host-virus interaction, isopeptide bond, metal-binding, nucleus, receptor, transcription, transcription regulation, zinc-finger, activator, phosphoprotein
Biological source	Homo sapiens (human)
Cellular location	Nucleus: P19793 Q15596
Total number of polymer chains	2
Total formula weight	29258.45
Authors	le Maire, A.,Bourguet, W. (deposition date: 2009-12-02, release date: 2010-01-19, Last modification date: 2023-09-06)
Primary citation	le Maire, A.,Bourguet, W.,Balaguer, P. A structural view of nuclear hormone receptor: endocrine disruptor interactions. Cell.Mol.Life Sci., 67:1219-1237, 2010 Cited by PubMed: 20063036 DOI: 10.1007/s00018-009-0249-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation