3KWA
Polyamines inhibit carbonic anhydrases
Summary for 3KWA
| Entry DOI | 10.2210/pdb3kwa/pdb |
| Descriptor | Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (5 entities in total) |
| Functional Keywords | polyamines, carbonic anhydrase ii, inhibition, lyase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm : P00918 |
| Total number of polymer chains | 1 |
| Total formula weight | 29757.40 |
| Authors | Temperini, C. (deposition date: 2009-12-01, release date: 2010-07-14, Last modification date: 2023-11-01) |
| Primary citation | Carta, F.,Temperini, C.,Innocenti, A.,Scozzafava, A.,Kaila, K.,Supuran, C.T. Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule J.Med.Chem., 53:5511-5522, 2010 Cited by PubMed: 20590092DOI: 10.1021/jm1003667 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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