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3KGV

Crystal Structure of Human DNA-dependent Protein Kinase Catalytic Subunit (DNA-PKcs)

Summary for 3KGV
Entry DOI10.2210/pdb3kgv/pdb
EMDB information1102 1208 1209 1210 1270 1271
DescriptorDNA-dependent Protein Kinase Catalytic Subunit (1 entity in total)
Functional Keywordsdna-dependent protein kinase catalytic subunit, dna-pkcs, ku80, non-homologues end joining, dna repair, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains14
Total formula weight4918806.82
Authors
Sibanda, B.L.,Chirgadze, D.Y.,Blundell, T.L. (deposition date: 2009-10-29, release date: 2009-12-22, Last modification date: 2024-03-20)
Primary citationSibanda, B.L.,Chirgadze, D.Y.,Blundell, T.L.
Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats.
Nature, 463:118-121, 2010
Cited by
PubMed: 20023628
DOI: 10.1038/nature08648
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (6.6 Å)
Structure validation

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