3KCY

Factor inhibiting HIF-1 alpha in complex with 8-hydroxyquinoline

Summary for 3KCY

• Entry DOI: 10.2210/pdb3kcy/pdb
• Related: 3KCX
• Descriptor: Hypoxia-inducible factor 1-alpha inhibitor, FE (II) ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: hypoxia, hif-1, fih-1, inhibitor, dioxygenase, iron, metal-binding, nucleus, oxidoreductase, transcription, transcription regulation
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q9NWT6
• Total number of polymer chains: 1
• Total formula weight: 39546.15

Authors

Moon, H.,Han, S.,Choe, J. (deposition date: 2009-10-22, release date: 2010-04-28, Last modification date: 2024-03-20)

• Primary citation: Moon, H.,Han, S.,Park, H.,Choe, J.; Crystal structures of human FIH-1 in complex with quinol family inhibitors; Mol.Cells, 29:471-474, 2010; PubMed: 20396966; DOI: 10.1007/s10059-010-0058-3

Experimental method

X-RAY DIFFRACTION (2.59 Å)