3KCX
Factor inhibiting HIF-1 alpha in complex with Clioquinol
Summary for 3KCX
Entry DOI | 10.2210/pdb3kcx/pdb |
Related | 3KCY |
Descriptor | Hypoxia-inducible factor 1-alpha inhibitor, FE (II) ION, SULFATE ION, ... (6 entities in total) |
Functional Keywords | hypoxia, hif-1, fih-1, inhibitor, dioxygenase, iron, metal-binding, nucleus, oxidoreductase, transcription, transcription regulation |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q9NWT6 |
Total number of polymer chains | 1 |
Total formula weight | 39982.77 |
Authors | |
Primary citation | Moon, H.,Han, S.,Park, H.,Choe, J. Crystal structures of human FIH-1 in complex with quinol family inhibitors Mol.Cells, 29:471-474, 2010 Cited by PubMed: 20396966DOI: 10.1007/s10059-010-0058-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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