3KAS

Machupo virus GP1 bound to human transferrin receptor 1

Summary for 3KAS

• Entry DOI: 10.2210/pdb3kas/pdb
• Related: 1CX8 2WFO
• Descriptor: Transferrin receptor protein 1, Glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: machupo virus, transferrin receptor 1, arenavirus, cell membrane, disulfide bond, endocytosis, glycoprotein, host-virus interaction, receptor, secreted, transmembrane, viral protein-endocytosis complex, viral protein/endocytosis
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 93729.71

Authors

Abraham, J.,Corbett, K.D.,Harrison, S.C. (deposition date: 2009-10-19, release date: 2010-03-09, Last modification date: 2023-09-06)

• Primary citation: Abraham, J.,Corbett, K.D.,Farzan, M.,Choe, H.,Harrison, S.C.; Structural basis for receptor recognition by New World hemorrhagic fever arenaviruses.; Nat.Struct.Mol.Biol., 17:438-444, 2010; PubMed: 20208545; DOI: 10.1038/nsmb.1772

Experimental method

X-RAY DIFFRACTION (2.4 Å)