3K9P

The crystal structure of E2-25K and ubiquitin complex

Summary for 3K9P

Entry DOI	10.2210/pdb3k9p/pdb
Related	3K9O
Descriptor	Ubiquitin-conjugating enzyme E2 K, Ubiquitin (2 entities in total)
Functional Keywords	e2-25k, ubiquitin, complex structure, atp-binding, isopeptide bond, ligase, nucleotide-binding, ubl conjugation pathway, nucleus, phosphoprotein, ligase-signaling protein complex, ligase/signaling protein
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm (By similarity): P61086
Total number of polymer chains	2
Total formula weight	32953.57
Authors	Kang, G.B.,Ko, S.,Song, S.M.,Lee, W.,Eom, S.H. (deposition date: 2009-10-16, release date: 2010-09-08, Last modification date: 2024-03-20)
Primary citation	Ko, S.,Kang, G.B.,Song, S.M.,Lee, J.-G.,Shin, D.Y.,Yun, J.-H.,Sheng, Y.,Cheong, C.,Jeon, Y.H.,Jung, Y.-K.,Arrowsmith, C.H.,Avvakumov, G.V.,Dhe-Paganon, S.,Yoo, Y.J.,Eom, S.H.,Lee, W. Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity J.Biol.Chem., 285:36070-36080, 2010 Cited by PubMed: 20826778 DOI: 10.1074/jbc.M110.145219 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation