3K7V

Protein phosphatase 2A core complex bound to dinophysistoxin-1

Summary for 3K7V

• Entry DOI: 10.2210/pdb3k7v/pdb
• Related: 2IE4 3K7W
• Descriptor: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, SULFATE ION, ... (6 entities in total)
• Functional Keywords: protein-protein complex, heat repeat, signaling protein, phosphatase, ligand specificity, acetylation, polymorphism, centromere, cytoplasm, cytoskeleton, hydrolase, iron, manganese, metal-binding, methylation, nucleus, phosphoprotein, protein phosphatase, signaling protein-hydrolase complex, signaling protein/hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm (By similarity): P30153; Cytoplasm: P67775
• Total number of polymer chains: 2
• Total formula weight: 102231.59

Authors

Jeffrey, P.D.,Huhn, J.,Shi, Y. (deposition date: 2009-10-13, release date: 2009-11-03, Last modification date: 2023-09-06)

• Primary citation: Huhn, J.,Jeffrey, P.D.,Larsen, K.,Rundberget, T.,Rise, F.,Cox, N.R.,Arcus, V.,Shi, Y.,Miles, C.O.; A structural basis for the reduced toxicity of dinophysistoxin-2.; Chem.Res.Toxicol., 22:1782-1786, 2009; PubMed: 19916524; DOI: 10.1021/tx9001622

Experimental method

X-RAY DIFFRACTION (2.85 Å)