3JVK

Crystal structure of bromodomain 1 of mouse Brd4 in complex with histone H3-K(ac)14

Summary for 3JVK

• Entry DOI: 10.2210/pdb3jvk/pdb
• Related: 3JVJ 3JVL 3JVM
• Descriptor: Bromodomain-containing protein 4, histone H3.3 peptide, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: bromodomain, alpha helical, n-acetyl lysine recognition, signaling protein
• Biological source: Mus musculus (mouse); More
• Cellular location: Nucleus: Q9ESU6 P84243
• Total number of polymer chains: 2
• Total formula weight: 16332.76

Authors

Vollmuth, F.,Blankenfeldt, W.,Geyer, M. (deposition date: 2009-09-17, release date: 2009-10-13, Last modification date: 2023-11-22)

• Primary citation: Vollmuth, F.,Blankenfeldt, W.,Geyer, M.; Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution; J.Biol.Chem., 284:36547-36556, 2009; PubMed: 19828451; DOI: 10.1074/jbc.M109.033712

Experimental method

X-RAY DIFFRACTION (1.8 Å)