3JR3

Sir2 bound to acetylated peptide

Summary for 3JR3

• Entry DOI: 10.2210/pdb3jr3/pdb
• Descriptor: NAD-dependent deacetylase, Acetylated Peptide, ZINC ION, ... (4 entities in total)
• Functional Keywords: sir2, deacetylation, nad+, ribosylation, hydrolase, metal-binding, nad
• Biological source: Thermotoga maritima
• Cellular location: Cytoplasm (By similarity): Q9WYW0
• Total number of polymer chains: 2
• Total formula weight: 29733.65

Authors

Hawse, W.F.,Wolberger, C. (deposition date: 2009-09-08, release date: 2009-09-29, Last modification date: 2023-11-22)

• Primary citation: Hawse, W.F.,Wolberger, C.; Structure-based mechanism of ADP-ribosylation by sirtuins.; J.Biol.Chem., 284:33654-33661, 2009; PubMed: 19801667; DOI: 10.1074/jbc.M109.024521

Experimental method

X-RAY DIFFRACTION (1.5 Å)