3JC7

Structure of the eukaryotic replicative CMG helicase and pumpjack motion

Summary for 3JC7

• Entry DOI: 10.2210/pdb3jc7/pdb
• Related: 3JC5 3JC6
• EMDB information: 6534 6535 6536
• Descriptor: DNA replication licensing factor MCM2, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF3, ... (12 entities in total)
• Functional Keywords: cmg helicase, cryo-em, hydrolase
• Biological source: Saccharomyces cerevisiae (yeast); More
• Total number of polymer chains: 11
• Total formula weight: 785823.29

Authors

Li, H.,Bai, L.,Yuan, Z.,Sun, J.,Georgescu, R.E.,Liu, J.,O'Donnell, M.E. (deposition date: 2015-11-24, release date: 2016-02-10, Last modification date: 2018-07-18)

• Primary citation: Yuan, Z.,Bai, L.,Sun, J.,Georgescu, R.,Liu, J.,O'Donnell, M.E.,Li, H.; Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.; Nat.Struct.Mol.Biol., 23:217-224, 2016; PubMed: 26854665; DOI: 10.1038/nsmb.3170

Experimental method

ELECTRON MICROSCOPY (4.8 Å)