3IVU

Homocitrate Synthase Lys4 bound to 2-OG

Summary for 3IVU

• Entry DOI: 10.2210/pdb3ivu/pdb
• Related: 3IVS 3IVT
• Descriptor: Homocitrate synthase, mitochondrial, COBALT (II) ION, SODIUM ION, ... (5 entities in total)
• Functional Keywords: tim barrel, metalloprotein, transferase, claisen condensation, amino-acid biosynthesis, lysine biosynthesis, mitochondrion, transit peptide
• Biological source: Schizosaccharomyces pombe (Fission yeast)
• Cellular location: Mitochondrion : Q9Y823
• Total number of polymer chains: 2
• Total formula weight: 93966.03

Authors

Bulfer, S.L.,Scott, E.M.,Couture, J.-F.,Pillus, L.,Trievel, R.C. (deposition date: 2009-09-01, release date: 2009-09-22, Last modification date: 2024-04-03)

• Primary citation: Bulfer, S.L.,Scott, E.M.,Couture, J.F.,Pillus, L.,Trievel, R.C.; Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis.; J.Biol.Chem., 284:35769-35780, 2009; PubMed: 19776021; DOI: 10.1074/jbc.M109.046821

Experimental method

X-RAY DIFFRACTION (2.72 Å)