3IRT
Crystal Structure of the I93M Mutant of Ubiquitin Carboxy-terminal Hydrolase L1
Summary for 3IRT
| Entry DOI | 10.2210/pdb3irt/pdb |
| Related | 2ETL |
| Descriptor | Ubiquitin carboxyl-terminal hydrolase isozyme L1, CHLORIDE ION (3 entities in total) |
| Functional Keywords | ubiquitin hydrolase, parkinson's disease mutant, cytoplasm, disease mutation, glycoprotein, hydrolase, ligase, oxidation, polymorphism, protease, thiol protease, ubl conjugation pathway |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P09936 |
| Total number of polymer chains | 2 |
| Total formula weight | 50640.58 |
| Authors | Davies, C.W.,Maiti, T.K.,Das, C. (deposition date: 2009-08-24, release date: 2010-06-09, Last modification date: 2023-09-06) |
| Primary citation | Boudreaux, D.A.,Maiti, T.K.,Davies, C.W.,Das, C. Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation. Proc.Natl.Acad.Sci.USA, 107:9117-9122, 2010 Cited by PubMed: 20439756DOI: 10.1073/pnas.0910870107 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.799 Å) |
Structure validation
Download full validation report
