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3ILB

Crystal structure of mouse Bcl-xl mutant (R139A) at pH 6.0

Summary for 3ILB
Entry DOI10.2210/pdb3ilb/pdb
Related3IHC 3IHD 3IHE 3IHF 3IIG 3IIH 3ILC
DescriptorBcl-2-like protein 1 (2 entities in total)
Functional Keywordsapoptosis, bh3 domain, bcl-2, membrane, mitochondrion, transmembrane
Biological sourceMus musculus (mouse)
Cellular locationMitochondrion membrane; Single-pass membrane protein. Isoform Bcl-X(L): Mitochondrion inner membrane. Isoform Bcl-X(delta-TM): Cytoplasm: Q64373
Total number of polymer chains2
Total formula weight43940.19
Authors
Priyadarshi, A.,Hwang, K.Y. (deposition date: 2009-08-07, release date: 2010-04-14, Last modification date: 2023-11-01)
Primary citationPriyadarshi, A.,Roy, A.,Kim, K.S.,Kim, E.E.,Hwang, K.Y.
Structural insights into mouse anti-apoptotic Bcl-xl reveal affinity for Beclin 1 and gossypol.
Biochem.Biophys.Res.Commun., 394:515-521, 2010
Cited by
PubMed: 20206602
DOI: 10.1016/j.bbrc.2010.03.002
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.38 Å)
Structure validation

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