3IJC

Crystal structure of Eed in complex with NDSB-195

Summary for 3IJC

Entry DOI	10.2210/pdb3ijc/pdb
Related	2QXV 3IIW 3IIY 3IJ0 3IJ1
Descriptor	Polycomb protein EED, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE (3 entities in total)
Functional Keywords	wd40 domain, alternative initiation, alternative splicing, chromatin regulator, nucleus, phosphoprotein, repressor, transcription, transcription regulation, wd repeat, gene regulation
Biological source	Homo sapiens (human)
Cellular location	Nucleus: O75530
Total number of polymer chains	1
Total formula weight	42335.20
Authors	Justin, N.,Sharpe, M.L.,Martin, S.,Taylor, W.R.,De Marco, V.,Gamblin, S.J. (deposition date: 2009-08-04, release date: 2009-09-15, Last modification date: 2024-04-03)
Primary citation	Margueron, R.,Justin, N.,Ohno, K.,Sharpe, M.L.,Son, J.,Drury, W.J.,Voigt, P.,Martin, S.R.,Taylor, W.R.,De Marco, V.,Pirrotta, V.,Reinberg, D.,Gamblin, S.J. Role of the polycomb protein EED in the propagation of repressive histone marks. Nature, 461:762-767, 2009 Cited by PubMed: 19767730 DOI: 10.1038/nature08398 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation