3IDO

Crystal structure of protein tyrosine phosphatase from Entamoeba histolytica with a phosphotyrosine crude mimic HEPES molecule in the active site

Summary for 3IDO

Entry DOI	10.2210/pdb3ido/pdb
Descriptor	Protein tyrosine phosphatase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID (3 entities in total)
Functional Keywords	niaid, ssgcid, seattle structural genomics center for infectious disease, parasitic protozoan, dysentery, hydrolase
Biological source	Entamoeba histolytica HM-1:IMSS
Total number of polymer chains	2
Total formula weight	41241.11
Authors	Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2009-07-21, release date: 2009-07-28, Last modification date: 2023-09-06)
Primary citation	Linford, A.S.,Jiang, N.M.,Edwards, T.E.,Sherman, N.E.,Van Voorhis, W.C.,Stewart, L.J.,Myler, P.J.,Staker, B.L.,Petri, W.A. Crystal structure and putative substrate identification for the Entamoeba histolytica low molecular weight tyrosine phosphatase. Mol.Biochem.Parasitol., 193:33-44, 2014 Cited by PubMed: 24548880 DOI: 10.1016/j.molbiopara.2014.01.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation