3IBC

Crystal Structure of Caspase-7 incomplex with Acetyl-YVAD-CHO

Summary for 3IBC

Entry DOI	10.2210/pdb3ibc/pdb
Descriptor	Caspase-7, Acetyl-YVAD-CHO, ... (4 entities in total)
Functional Keywords	protein-peptide complex, alternative splicing, apoptosis, cytoplasm, hydrolase, polymorphism, protease, thiol protease, zymogen
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: P55210 P55210
Total number of polymer chains	6
Total formula weight	62819.97
Authors	Agniswamy, J. (deposition date: 2009-07-15, release date: 2009-09-01, Last modification date: 2023-09-06)
Primary citation	Agniswamy, J.,Fang, B.,Weber, I.T. Conformational similarity in the activation of caspase-3 and -7 revealed by the unliganded and inhibited structures of caspase-7. Apoptosis, 14:1135-1144, 2009 Cited by PubMed: 19655253 DOI: 10.1007/s10495-009-0388-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation