3I59

Crystal structure of MtbCRP in complex with N6-cAMP

Summary for 3I59

• Entry DOI: 10.2210/pdb3i59/pdb
• Related: 3I54
• Descriptor: Transcriptional regulator, Crp/Fnr family, (2R)-N6-(1-Methyl-2-phenylethyl)adenosine-3',5'-cyclic monophosphate, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: mycobacterium tuberculosis, camp receptor protein, crp, allosteric mechanism, dna binding, inhibition, n6-camp, structural genomics, tb structural genomics consortium, tbsgc, dna-binding, transcription, transcription regulation, dna binding protein
• Biological source: Mycobacterium tuberculosis; More
• Total number of polymer chains: 2
• Total formula weight: 56171.70

Authors

Reddy, M.C.,Palaninathan, S.K.,Bruning, J.B.,Thurman, C.,Smith, D.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2009-07-03, release date: 2009-09-08, Last modification date: 2023-11-22)

• Primary citation: Reddy, M.C.,Palaninathan, S.K.,Bruning, J.B.,Thurman, C.,Smith, D.,Sacchettini, J.C.; Structural Insights into the Mechanism of the Allosteric Transitions of Mycobacterium tuberculosis cAMP Receptor Protein.; J.Biol.Chem., 284:36581-36591, 2009; PubMed: 19740754; DOI: 10.1074/jbc.M109.041343

Experimental method

X-RAY DIFFRACTION (2.29 Å)