3I49

Crystal Structure of AlkB in complex with Fe(II), 2-oxoglutarate and methylated trinucleotide T-meC-T

Summary for 3I49

• Entry DOI: 10.2210/pdb3i49/pdb
• Related: 2IUW 3BUC 3I2O 3I3M 3I3Q
• Descriptor: Alpha-ketoglutarate-dependent dioxygenase alkB, DNA (5'-D(P*TP*(ME6)P*T)-3'), 2-OXOGLUTARIC ACID, ... (5 entities in total)
• Functional Keywords: beta jellyroll, protein-dna complex, dioxygenase, dna damage, dna repair, iron, metal-binding, oxidoreductase, oxidoreductase-dna complex, oxidoreductase/dna
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 24680.56

Authors

Yu, B.,Hunt, J.F. (deposition date: 2009-07-01, release date: 2009-08-25, Last modification date: 2024-02-21)

• Primary citation: Yu, B.,Hunt, J.F.; Enzymological and structural studies of the mechanism of promiscuous substrate recognition by the oxidative DNA repair enzyme AlkB.; Proc.Natl.Acad.Sci.USA, 106:14315-14320, 2009; PubMed: 19706517; DOI: 10.1073/pnas.0812938106

Experimental method

X-RAY DIFFRACTION (1.6 Å)