3HX4

Crystal structure of CDPK1 of Toxoplasma gondii, TGME49_101440, in presence of calcium

Summary for 3HX4

Entry DOI	10.2210/pdb3hx4/pdb
Descriptor	Calmodulin-domain protein kinase 1, CALCIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (6 entities in total)
Functional Keywords	cdpks, toxoplasma, kinase, protist, structural genomics, structural genomics consortium, sgc, atp-binding, nucleotide-binding, serine/threonine-protein kinase, transferase
Biological source	Toxoplasma gondii
Total number of polymer chains	1
Total formula weight	58721.10
Authors	Wernimont, A.K.,Artz, J.D.,Finnerty, P.,Xiao, T.,He, H.,MacKenzie, F.,Sinestera, G.,Hassani, A.A.,Wasney, G.,Vedadi, M.,Lourido, S.,Bochkarev, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Sibley, D.L.,Hui, R.,Lin, Y.H.,Structural Genomics Consortium (SGC) (deposition date: 2009-06-19, release date: 2009-07-21, Last modification date: 2024-02-21)
Primary citation	Wernimont, A.K.,Artz, J.D.,Finerty, P.,Lin, Y.H.,Amani, M.,Allali-Hassani, A.,Senisterra, G.,Vedadi, M.,Tempel, W.,Mackenzie, F.,Chau, I.,Lourido, S.,Sibley, L.D.,Hui, R. Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium. Nat.Struct.Mol.Biol., 17:596-601, 2010 Cited by PubMed: 20436473 DOI: 10.1038/nsmb.1795 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation