3HUG

Crystal structure of Mycobacterium tuberculosis anti-sigma factor RslA in complex with -35 promoter binding domain of sigL

Summary for 3HUG

Entry DOI	10.2210/pdb3hug/pdb
Descriptor	RNA polymerase sigma factor, PROBABLE CONSERVED MEMBRANE PROTEIN, SULFATE ION, ... (5 entities in total)
Functional Keywords	ecf sigma factor, zinc binding anti-sigma factor, oxidative stress, transcription regulation, dna binding, metal binding, hxxxcxxc motif, dna-binding, sigma factor, transcription, transcription-membrane protein complex, transcription/membrane protein
Biological source	Mycobacterium tuberculosis More
Total number of polymer chains	20
Total formula weight	217456.48
Authors	Thakur, K.G.,Gopal, B. (deposition date: 2009-06-14, release date: 2010-03-02, Last modification date: 2024-03-20)
Primary citation	Thakur, K.G.,Praveena, T.,Gopal, B. Structural and biochemical bases for the redox sensitivity of Mycobacterium tuberculosis RslA J.Mol.Biol., 397:1199-1208, 2010 Cited by PubMed: 20184899 DOI: 10.1016/j.jmb.2010.02.026 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation