3HSV

Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep2

Summary for 3HSV

Entry DOI	10.2210/pdb3hsv/pdb
Related	3HQI 3HQL 3HQM 3HTM 3HU6 3HVE
Descriptor	Speckle-type POZ protein, Core histone macro-H2A.1, ZINC ION, ... (5 entities in total)
Functional Keywords	ubiquitin, e3, spop, macroh2a, nucleus, ubl conjugation pathway, alternative splicing, chromatin regulator, chromosomal protein, dna-binding, isopeptide bond, methylation, nucleosome core, phosphoprotein, ubl conjugation, ligase, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	34800.75
Authors	Zhuang, M.,Schulman, B.A.,Miller, D. (deposition date: 2009-06-10, release date: 2009-10-20, Last modification date: 2023-09-06)
Primary citation	Zhuang, M.,Calabrese, M.F.,Liu, J.,Waddell, M.B.,Nourse, A.,Hammel, M.,Miller, D.J.,Walden, H.,Duda, D.M.,Seyedin, S.N.,Hoggard, T.,Harper, J.W.,White, K.P.,Schulman, B.A. Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. Mol.Cell, 36:39-50, 2009 Cited by PubMed: 19818708 DOI: 10.1016/j.molcel.2009.09.022 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.43 Å)

Structure validation