3HQG

Crystal structure of restriction endonuclease EcoRII catalytic C-terminal domain in complex with cognate DNA

Summary for 3HQG

• Entry DOI: 10.2210/pdb3hqg/pdb
• Related: 1na6 3HQF
• Descriptor: Type-2 restriction enzyme EcoRII, 5'-D(*TP*CP*GP*AP*CP*CP*AP*GP*GP*CP*TP*A)-3', 5'-D(*TP*AP*GP*CP*CP*TP*GP*GP*TP*CP*GP*A)-3', ... (5 entities in total)
• Functional Keywords: restriction endonuclease, ecorii, nucleotide flipping, protein-dna complex, dna recognition, endonuclease, hydrolase, magnesium, nuclease, restriction system, hydrolase-dna complex, hydrolase/dna
• Biological source: Escherichia coli
• Total number of polymer chains: 3
• Total formula weight: 32995.08

Authors

Golovenko, D.,Manakova, E.,Grazulis, S.,Tamulaitiene, G.,Siksnys, V. (deposition date: 2009-06-06, release date: 2009-09-22, Last modification date: 2023-09-06)

• Primary citation: Golovenko, D.,Manakova, E.,Tamulaitiene, G.,Grazulis, S.,Siksnys, V.; Structural mechanisms for the 5'-CCWGG sequence recognition by the N- and C-terminal domains of EcoRII.; Nucleic Acids Res., 37:6613-6624, 2009; PubMed: 19729506; DOI: 10.1093/nar/gkp699

Experimental method

X-RAY DIFFRACTION (2.6 Å)