Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3HPH

Closed tetramer of Visna virus integrase (residues 1-219) in complex with LEDGF IBD

Summary for 3HPH
Entry DOI10.2210/pdb3hph/pdb
Related1K6Y 2B4J 3F9K 3HPG
DescriptorIntegrase, PC4 and SFRS1-interacting protein, ZINC ION, ... (6 entities in total)
Functional Keywordsprotein-protein complex, tetramer, dna integration, endonuclease, magnesium, metal-binding, multifunctional enzyme, nuclease, nucleotidyltransferase, nucleus, transferase, viral nucleoprotein, virion, dna-binding, host-virus interaction, transcription, transcription regulation, zinc binding, hhcc motif, viral protein, recombination
Biological sourceMaedi visna virus (MVV)
More
Cellular locationNucleus: O75475
Total number of polymer chains8
Total formula weight145232.32
Authors
Hare, S.,Wang, J.,Cherepanov, P. (deposition date: 2009-06-04, release date: 2009-07-28, Last modification date: 2023-11-01)
Primary citationHare, S.,Di Nunzio, F.,Labeja, A.,Wang, J.,Engelman, A.,Cherepanov, P.
Structural basis for functional tetramerization of lentiviral integrase
Plos Pathog., 5:e1000515-e1000515, 2009
Cited by
PubMed: 19609359
DOI: 10.1371/journal.ppat.1000515
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.64 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon