3HO1
Crystal structure of T. thermophilus Argonaute N546 mutant protein complexed with DNA guide strand and 12-nt RNA target strand
Summary for 3HO1
Entry DOI | 10.2210/pdb3ho1/pdb |
Related | 3DLB 3DLH 3F73 3HGE 3HJF 3HK2 |
Descriptor | argonaute, 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*T*AP*GP*T)-3', 5'-R(P*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', ... (5 entities in total) |
Functional Keywords | argonaute, protein-dna-rna complex, nucleic acid binding protein-dna-rna complex, nucleic acid binding protein/dna/rna |
Biological source | Thermus thermophilus |
Total number of polymer chains | 3 |
Total formula weight | 87048.57 |
Authors | Wang, Y.,Li, H.,Sheng, G.,Patel, D.J. (deposition date: 2009-06-01, release date: 2009-10-06, Last modification date: 2023-09-06) |
Primary citation | Wang, Y.,Juranek, S.,Li, H.,Sheng, G.,Wardle, G.S.,Tuschl, T.,Patel, D.J. Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. Nature, 461:754-761, 2009 Cited by PubMed: 19812667DOI: 10.1038/nature08434 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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