3HII

Crystal structure of human diamine oxidase in complex with the inhibitor pentamidine

Summary for 3HII

Entry DOI	10.2210/pdb3hii/pdb
Related	3HI7 3HIG
Descriptor	Amiloride-sensitive amine oxidase, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	oxidoreductase, copper amine oxidase, topaquinone, tpq, diamine oxidase, dao, human, pentamidine, glycoprotein, heparin-binding, metal-binding, secreted
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	170696.48
Authors	McGrath, A.P.,Guss, J.M. (deposition date: 2009-05-20, release date: 2009-10-20, Last modification date: 2023-11-01)
Primary citation	McGrath, A.P.,Hilmer, K.M.,Collyer, C.A.,Shepard, E.M.,Elmore, B.O.,Brown, D.E.,Dooley, D.M.,Guss, J.M. Structure and inhibition of human diamine oxidase Biochemistry, 48:9810-9822, 2009 Cited by PubMed: 19764817 DOI: 10.1021/bi9014192 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.149 Å)

Structure validation