3HH7

Structural and Functional Characterization of a Novel Homodimeric Three-finger Neurotoxin from the Venom of Ophiophagus hannah (King Cobra)

Summary for 3HH7

Entry DOI	10.2210/pdb3hh7/pdb
Descriptor	Muscarinic toxin-like protein 3 homolog (2 entities in total)
Functional Keywords	haditoxin, three finger toxin, ophiophagus hannah, snake venom, neurotoxin, nicotinic acetylcholine receptors, acetylcholine receptor inhibitor, disulfide bond, postsynaptic neurotoxin, secreted, toxin
Biological source	Ophiophagus hannah (King cobra)
Cellular location	Secreted : A8N286
Total number of polymer chains	2
Total formula weight	15104.88
Authors	Roy, A.,Zhou, X.,Chong, M.Z.,D'hoedt, D.,Foo, C.S.,Rajagopalan, N.,Nirthanan, S.,Bertrand, D.,Sivaraman, J.,Kini, R.M. (deposition date: 2009-05-15, release date: 2010-01-12, Last modification date: 2017-11-01)
Primary citation	Roy, A.,Zhou, X.,Chong, M.Z.,D'hoedt, D.,Foo, C.S.,Rajagopalan, N.,Nirthanan, S.,Bertrand, D.,Sivaraman, J.,Kini, R.M. Structural and Functional Characterization of a Novel Homodimeric Three-finger Neurotoxin from the Venom of Ophiophagus hannah (King Cobra) J.Biol.Chem., 285:8302-8315, 2010 Cited by PubMed: 20071329 DOI: 10.1074/jbc.M109.074161 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation