3HCU

Crystal structure of TRAF6 in complex with Ubc13 in the C2 space group

Summary for 3HCU

• Entry DOI: 10.2210/pdb3hcu/pdb
• Related: 3HCS 3HCT
• Descriptor: TNF receptor-associated factor 6, Ubiquitin-conjugating enzyme E2 N, ZINC ION, ... (4 entities in total)
• Functional Keywords: cross-brace, beta-beta-alpha, coiled coil, cytoplasm, metal-binding, ubl conjugation, ubl conjugation pathway, zinc, zinc-finger, atp-binding, dna damage, dna repair, isopeptide bond, ligase, nucleotide-binding, signaling protein-ligase complex, signaling protein/ligase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : Q9Y4K3; Nucleus : P61088
• Total number of polymer chains: 4
• Total formula weight: 62824.36

Authors

Yin, Q.,Lin, S.-C.,Lamothe, B.,Lu, M.,Lo, Y.-C.,Hura, G.,Zheng, L.,Rich, R.L.,Campos, A.D.,Myszka, D.G.,Lenardo, M.J.,Darnay, B.G.,Wu, H. (deposition date: 2009-05-06, release date: 2009-05-26, Last modification date: 2023-09-06)

• Primary citation: Yin, Q.,Lin, S.C.,Lamothe, B.,Lu, M.,Lo, Y.C.,Hura, G.,Zheng, L.,Rich, R.L.,Campos, A.D.,Myszka, D.G.,Lenardo, M.J.,Darnay, B.G.,Wu, H.; E2 interaction and dimerization in the crystal structure of TRAF6.; Nat.Struct.Mol.Biol., 16:658-666, 2009; PubMed: 19465916; DOI: 10.1038/nsmb.1605

Experimental method

X-RAY DIFFRACTION (2.6 Å)