3HCF
Crystal Structure of hPNMT in Complex With 3-trifluoromethyl phenylethanolamine and AdoHcy
Summary for 3HCF
| Entry DOI | 10.2210/pdb3hcf/pdb |
| Related | 1HNN 1N7I 1N7J 1YZ3 2AN3 2AN4 2AN5 2G70 2G71 2G72 2G8N 2OBF 2ONY 2ONZ 2OPB 3HCA 3HCB 3HCC 3HCD 3HCE |
| Descriptor | Phenylethanolamine N-methyltransferase, (1R)-2-amino-1-[3-(trifluoromethyl)phenyl]ethanol, S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total) |
| Functional Keywords | methyltransferase, catecholamine biosynthesis, polymorphism, s-adenosyl-l-methionine, transferase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 64933.18 |
| Authors | Drinkwater, N.,Martin, J.L. (deposition date: 2009-05-06, release date: 2009-08-25, Last modification date: 2023-09-06) |
| Primary citation | Drinkwater, N.,Gee, C.L.,Puri, M.,Criscione, K.R.,McLeish, M.J.,Grunewald, G.L.,Martin, J.L. Molecular recognition of physiological substrate noradrenaline by the adrenaline-synthesizing enzyme PNMT and factors influencing its methyltransferase activity. Biochem.J., 422:463-471, 2009 Cited by PubMed: 19570037DOI: 10.1042/BJ20090702 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.702 Å) |
Structure validation
Download full validation report
