3H91

Crystal structure of the complex of human chromobox homolog 2 (CBX2) and H3K27 peptide

Summary for 3H91

Entry DOI	10.2210/pdb3h91/pdb
Descriptor	Chromobox protein homolog 2, H3K27 peptide (3 entities in total)
Functional Keywords	human chromobox homolog 2, cbx2, h3k27, structural genomics, structural genomics consortium, sgc, chromatin regulator, dna-binding, nucleus, repressor, transcription, transcription regulation
Biological source	Homo sapiens (human)
Cellular location	Nucleus : Q14781
Total number of polymer chains	4
Total formula weight	16054.66
Authors	Amaya, M.F.,Ravichandran, M.,Loppnau, P.,Kozieradzki, I.,Edwards, A.M.,Arrowsmith, C.H.,Weigelt, J.,Bountra, C.,Bochkarev, A.,Min, J.,Ouyang, H.,Structural Genomics Consortium (SGC) (deposition date: 2009-04-29, release date: 2009-08-18, Last modification date: 2017-11-01)
Primary citation	Kaustov, L.,Ouyang, H.,Amaya, M.,Lemak, A.,Nady, N.,Duan, S.,Wasney, G.A.,Li, Z.,Vedadi, M.,Schapira, M.,Min, J.,Arrowsmith, C.H. Recognition and specificity determinants of the human cbx chromodomains. J.Biol.Chem., 286:521-529, 2011 Cited by PubMed: 21047797 DOI: 10.1074/jbc.M110.191411 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation