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3H30

Crystal structure of the catalytic subunit of human protein kinase CK2 with 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole

Replaces:  2RKP
Summary for 3H30
Entry DOI10.2210/pdb3h30/pdb
Related1JWH 1LP4 2PVR
DescriptorCasein kinase II subunit alpha, 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsprotein kinase ck2, casein kinase 2, casein kinase ii, atp-binding, kinase, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase, wnt signaling pathway
Biological sourceHomo sapiens (human)
Cellular locationNucleus : P68400
Total number of polymer chains2
Total formula weight82111.30
Authors
Niefind, K.,Raaf, J.,Issinger, O.-G. (deposition date: 2009-04-15, release date: 2009-05-12, Last modification date: 2024-03-20)
Primary citationRaaf, J.,Brunstein, E.,Issinger, O.-G.,Niefind, K.
The CK2alpha/CK2beta Interface of Human Protein Kinase CK2 Harbors a Binding Pocket for Small Molecules
Chem.Biol., 15:111-117, 2008
Cited by
PubMed: 18291315
DOI: 10.1016/j.chembiol.2007.12.012
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.56 Å)
Structure validation

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