3GXU

Crystal structure of Eph receptor and ephrin complex

Summary for 3GXU

Entry DOI	10.2210/pdb3gxu/pdb
Descriptor	Ephrin type-A receptor 4, Ephrin-B2 (3 entities in total)
Functional Keywords	complex structure, eph, ephrin, atp-binding, glycoprotein, kinase, membrane, nucleotide-binding, phosphoprotein, receptor, transferase, transmembrane, tyrosine-protein kinase, developmental protein, differentiation, disulfide bond, host-virus interaction, neurogenesis
Biological source	Homo sapiens (human) More
Cellular location	Cell membrane; Single-pass type I membrane protein (By similarity): P54764 Membrane; Single-pass type I membrane protein: P52799
Total number of polymer chains	2
Total formula weight	36468.37
Authors	Qin, H.N.,Song, J.X. (deposition date: 2009-04-03, release date: 2009-10-27, Last modification date: 2023-11-01)
Primary citation	Qin, H.,Noberini, R.,Huan, X.,Shi, J.,Pasquale, E.B.,Song, J. Structural characterization of the EphA4-ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity J.Biol.Chem., 2009 Cited by PubMed: 19875447 DOI: 10.1074/jbc.M109.064824 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation