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3GG3

Crystal Structure of the Bromodomain of Human PCAF

Summary for 3GG3
Entry DOI10.2210/pdb3gg3/pdb
DescriptorHistone acetyltransferase PCAF, CHLORIDE ION (3 entities in total)
Functional Keywordspcaf, k(lysine) acetyltransferase 2b, kat2b, gcn5, gcn5l, p, p/caf, crebbp-associated factor, p300/cbp-associated factor, sgc, structural genomics consortium, acyltransferase, bromodomain, cell cycle, host-virus interaction, nucleus, phosphoprotein, transcription, transcription regulation, transferase
Biological sourceHomo sapiens (Human)
Cellular locationNucleus : Q92831
Total number of polymer chains2
Total formula weight28380.19
Authors
Primary citationFilippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S.
Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149:214-231, 2012
Cited by
PubMed: 22464331
DOI: 10.1016/j.cell.2012.02.013
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.25 Å)
Structure validation

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