3GD8

Crystal Structure of Human Aquaporin 4 at 1.8 and its Mechanism of Conductance

Summary for 3GD8

Entry DOI	10.2210/pdb3gd8/pdb
Descriptor	Aquaporin-4, GLYCEROL, octyl beta-D-glucopyranoside, ... (4 entities in total)
Functional Keywords	brain edema, aquaporin, proton exclusion, structural genomics, psi-2, protein structure initiative, center for structures of membrane proteins, csmp, glycoprotein, membrane, phosphoprotein, transmembrane, transport, membrane protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	24279.58
Authors	Ho, J.D.,Yeh, R.,Sandstrom, A.,Chorny, I.,Harries, W.E.C.,Robbins, R.A.,Miercke, L.J.W.,Stroud, R.M.,Center for Structures of Membrane Proteins (CSMP) (deposition date: 2009-02-23, release date: 2009-03-31, Last modification date: 2024-02-21)
Primary citation	Ho, J.D.,Yeh, R.,Sandstrom, A.,Chorny, I.,Harries, W.E.,Robbins, R.A.,Miercke, L.J.,Stroud, R.M. Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance. Proc.Natl.Acad.Sci.USA, 106:7437-7442, 2009 Cited by PubMed: 19383790 DOI: 10.1073/pnas.0902725106 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation