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3GAX

Crystal structure of monomeric human cystatin C stabilized against aggregation

Summary for 3GAX
Entry DOI10.2210/pdb3gax/pdb
Related1G96 1R4C 1TIJ
DescriptorCystatin-C (2 entities in total)
Functional Keywordscysteine protease inhibitor, 3d domain swapping, protein aggregation, amyloid, protein engineering, twinning, hereditary cystatin c amyloid angiopathy, amyloidosis, disease mutation, polymorphism, protease inhibitor, secreted, thiol protease inhibitor, hydrolase inhibitor
Biological sourceHomo sapiens (Human)
Cellular locationSecreted : P01034
Total number of polymer chains2
Total formula weight26802.43
Authors
Kolodziejczyk, R.,Michalska, K.,Hernandez-Santoyo, A.,Wahlbom, M.,Grubb, A.,Jaskolski, M. (deposition date: 2009-02-18, release date: 2010-02-23, Last modification date: 2023-09-06)
Primary citationKolodziejczyk, R.,Michalska, K.,Hernandez-Santoyo, A.,Wahlbom, M.,Grubb, A.,Jaskolski, M.
Crystal structure of human cystatin C stabilized against amyloid formation.
Febs J., 277:1726-1737, 2010
Cited by
PubMed: 20175878
DOI: 10.1111/j.1742-4658.2010.07596.x
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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