3G6X

Ternary complex of DNA Polymerase iota:DNA:dGTP with an abasic site at the templating position

Summary for 3G6X

Entry DOI	10.2210/pdb3g6x/pdb
Related	2fll 3g6v 3g6y
Descriptor	DNA polymerase iota, Primer DNA strand, Template DNA strand, ... (6 entities in total)
Functional Keywords	dna polymerase, y-family, lesion bypass, abasic site, ternary complex, dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, nucleus, schiff base, transferase, replication-dna complex, replication/dna
Biological source	Homo sapiens (human)
Total number of polymer chains	3
Total formula weight	52881.62
Authors	Nair, D.T.,Aggarwal, A.K. (deposition date: 2009-02-09, release date: 2009-05-12, Last modification date: 2023-09-06)
Primary citation	Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. DNA Synthesis across an Abasic Lesion by Human DNA Polymerase iota. Structure, 17:530-537, 2009 Cited by PubMed: 19368886 DOI: 10.1016/j.str.2009.02.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.08 Å)

Structure validation