3G6Q

GR DNA binding domain:FKBP5 binding site complex-9

Summary for 3G6Q

• Entry DOI: 10.2210/pdb3g6q/pdb
• Related: 3FYL 3G6P 3G6R 3G6T 3G6U 3G8X 3G97 3G99
• Descriptor: Glucocorticoid receptor, DNA (5'-D(*TP*AP*GP*AP*AP*CP*AP*GP*GP*GP*TP*GP*TP*TP*CP*T)-3'), DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*CP*CP*CP*TP*GP*TP*TP*CP*T)-3'), ... (5 entities in total)
• Functional Keywords: glucocorticoid, dna-binding, allostery, lever arm, transcription, hormone, alternative initiation, chromatin regulator, cytoplasm, lipid-binding, metal-binding, nucleus, phosphoprotein, polymorphism, receptor, steroid-binding, transcription regulation, ubl conjugation, zinc, zinc-finger, transcription-dna complex, transcription/dna
• Biological source: Rattus norvegicus (brown rat,rat,rats)
• Cellular location: Isoform A: Cytoplasm : P06536
• Total number of polymer chains: 4
• Total formula weight: 29982.55

Authors

Pufall, M.A.,Yamamoto, K.R.,Meijsing, S.H. (deposition date: 2009-02-08, release date: 2009-04-21, Last modification date: 2023-09-06)

• Primary citation: Meijsing, S.H.,Pufall, M.A.,So, A.Y.,Bates, D.L.,Chen, L.,Yamamoto, K.R.; DNA binding site sequence directs glucocorticoid receptor structure and activity.; Science, 324:407-410, 2009; PubMed: 19372434; DOI: 10.1126/science.1164265

Experimental method

X-RAY DIFFRACTION (2.26 Å)