3FX4
Porcine aldehyde reductase in ternary complex with inhibitor
Summary for 3FX4
| Entry DOI | 10.2210/pdb3fx4/pdb |
| Related | 2AO0 3CV7 |
| Descriptor | Alcohol dehydrogenase [NADP+], SULFATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
| Functional Keywords | tim barrel, aldo-keto reductase, ternary complex, acetylation, nadp, oxidoreductase |
| Biological source | Sus scrofa (Pig) |
| Total number of polymer chains | 1 |
| Total formula weight | 38025.88 |
| Authors | Carbone, V.,El-Kabbani, O. (deposition date: 2009-01-20, release date: 2009-12-22, Last modification date: 2023-11-01) |
| Primary citation | Carbone, V.,Giglio, M.,Chung, R.,Huyton, T.,Adams, J.,Maccari, R.,Ottana, R.,Hara, A.,El-Kabbani, O. Structure of aldehyde reductase in ternary complex with a 5-arylidene-2,4-thiazolidinedione aldose reductase inhibitor. Eur.J.Med.Chem., 45:1140-1145, 2010 Cited by PubMed: 20036445DOI: 10.1016/j.ejmech.2009.12.019 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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