3FVZ

Structure of Peptidyl-alpha-hydroxyglycine alpha-Amidating Lyase (PAL)

Summary for 3FVZ

Entry DOI	10.2210/pdb3fvz/pdb
Related	1PHM 3FW0
Descriptor	Peptidyl-glycine alpha-amidating monooxygenase, ZINC ION, FE (III) ION, ... (7 entities in total)
Functional Keywords	beta propeller, lyase, peptide amidation, hg-mad, zn-mad, cleavage on pair of basic residues, cytoplasmic vesicle, glycoprotein, membrane, metal-binding, monooxygenase, multifunctional enzyme, oxidoreductase, phosphoprotein, sulfation, transmembrane, vitamin c
Biological source	Rattus norvegicus (brown rat,rat,rats)
Cellular location	Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein: P14925
Total number of polymer chains	1
Total formula weight	37318.65
Authors	Chufan, E.E.,De, M.,Eipper, B.A.,Mains, R.E.,Amzel, L.M. (deposition date: 2009-01-16, release date: 2009-09-01, Last modification date: 2011-07-13)
Primary citation	Chufan, E.E.,De, M.,Eipper, B.A.,Mains, R.E.,Amzel, L.M. Amidation of bioactive peptides: the structure of the lyase domain of the amidating enzyme. Structure, 17:965-973, 2009 Cited by PubMed: 19604476 DOI: 10.1016/j.str.2009.05.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation