Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3FR2

N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte Fatty-Acid Binding Protein (A-FABP) inhibitors

Summary for 3FR2
Entry DOI10.2210/pdb3fr2/pdb
Related3FR4 3FR5
DescriptorFatty acid-binding protein, adipocyte, 9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid (3 entities in total)
Functional Keywordsselective adipocyte fatty-acid binding protein (a-fabp) inhibitors, cytoplasm, lipid-binding, nucleus, phosphoprotein, polymorphism, transport, lipid binding protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P15090
Total number of polymer chains1
Total formula weight14914.07
Authors
Barf, T.,Hammer, K.,Lehmann, F.,Haile, S.,Axen, E.,Medina, C.,Rondahl, L.,Uppenberg, J.,Svensson, S.,Lundb ck, T. (deposition date: 2009-01-08, release date: 2009-03-10, Last modification date: 2024-02-21)
Primary citationBarf, T.,Lehmann, F.,Hammer, K.,Haile, S.,Axen, E.,Medina, C.,Uppenberg, J.,Svensson, S.,Rondahl, L.,Lundback, T.
N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors.
Bioorg.Med.Chem.Lett., 19:1745-1748, 2009
Cited by
PubMed: 19217286
DOI: 10.1016/j.bmcl.2009.01.084
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon