3FNV
Crystal Structure of Miner1: The Redox-active 2Fe-2S Protein Causative in Wolfram Syndrome 2
Summary for 3FNV
Entry DOI | 10.2210/pdb3fnv/pdb |
Related | 2QH7 |
Descriptor | CDGSH iron sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER (3 entities in total) |
Functional Keywords | diabetes, membrane bound, thiazolidinedione, oxidative stress, cdgsh, endoplasmic reticulum, iron, iron-sulfur, membrane, metal-binding, transmembrane, zinc-finger, metal binding protein |
Biological source | Homo sapiens (Human) |
Cellular location | Endoplasmic reticulum membrane; Single-pass membrane protein: Q8N5K1 |
Total number of polymer chains | 2 |
Total formula weight | 19331.73 |
Authors | Conlan, A.R.,Axelrod, H.L.,Cohen, A.E.,Abresch, E.C.,Yee, D.,Zuris, J.,Nechushtai, R.,Jennings, P.A.,Paddock, M.L. (deposition date: 2008-12-26, release date: 2009-08-18, Last modification date: 2024-02-21) |
Primary citation | Conlan, A.R.,Axelrod, H.L.,Cohen, A.E.,Abresch, E.C.,Zuris, J.,Yee, D.,Nechushtai, R.,Jennings, P.A.,Paddock, M.L. Crystal structure of Miner1: The redox-active 2Fe-2S protein causative in Wolfram Syndrome 2. J.Mol.Biol., 392:143-153, 2009 Cited by PubMed: 19580816DOI: 10.1016/j.jmb.2009.06.079 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report