3FLO

Crystal structure of the carboxyl-terminal domain of yeast DNA polymerase alpha in complex with its B subunit

Summary for 3FLO

Entry DOI	10.2210/pdb3flo/pdb
Descriptor	DNA polymerase alpha subunit B, DNA polymerase alpha catalytic subunit A, SULFATE ION, ... (6 entities in total)
Functional Keywords	protein-protein complex, phosphoesterase fold, ob fold, zinc-binding motif, dna replication, nucleus, phosphoprotein, dna-binding, dna-directed dna polymerase, nucleotidyltransferase, transferase
Biological source	Saccharomyces cerevisiae (Baker's yeast) More
Cellular location	Nucleus: P38121 P13382
Total number of polymer chains	12
Total formula weight	311633.59
Authors	Klinge, S.N.,Pellegrini, L. (deposition date: 2008-12-19, release date: 2009-06-09, Last modification date: 2024-03-20)
Primary citation	Klinge, S.,Nunez-Ramirez, R.,Llorca, O.,Pellegrini, L. 3D architecture of DNA Pol alpha reveals the functional core of multi-subunit replicative polymerases Embo J., 28:1978-1987, 2009 Cited by PubMed: 19494830 DOI: 10.1038/emboj.2009.150 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation