3FHI
Crystal structure of a complex between the catalytic and regulatory (RI{alpha}) subunits of PKA
Replaces: 1U7ESummary for 3FHI
Entry DOI | 10.2210/pdb3fhi/pdb |
Descriptor | cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type I-alpha regulatory subunit, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total) |
Functional Keywords | camp, camp dependent protein kinase, protein-protein complex, amp-pnp, protein kinase regulation, nucleotide binding, protein kinase activity, protein serine/threonine kinase activity, camp-dependent protein kinase activity, protein binding, atp binding, kinase activity, transferase activity, atp-binding, kinase, lipoprotein, myristate, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase, camp-binding |
Biological source | Mus musculus (mouse) More |
Cellular location | Cytoplasm . Isoform 2: Cell projection, cilium, flagellum : P05132 Cell membrane : P00514 |
Total number of polymer chains | 2 |
Total formula weight | 58580.89 |
Authors | |
Primary citation | Kim, C.,Xuong, N.H.,Taylor, S.S. Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA. Science, 307:690-696, 2005 Cited by PubMed: 15692043DOI: 10.1126/science.1104607 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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