3FGA

Structural Basis of PP2A and Sgo interaction

Summary for 3FGA

Entry DOI	10.2210/pdb3fga/pdb
Related PRD ID	PRD_000212
Descriptor	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ... (7 entities in total)
Functional Keywords	pp2a, shugoshin, nucleus, phosphoprotein, hydrolase, iron, manganese, metal-binding, methylation, protein phosphatase, cell cycle, cell division, centromere, chromosome partition, mitosis, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Mus musculus (mouse) More
Cellular location	Cytoplasm : Q76MZ3 P67775 Nucleus: Q13362 Q5FBB7
Total number of polymer chains	5
Total formula weight	155274.26
Authors	Xu, Z.,Xu, W. (deposition date: 2008-12-05, release date: 2009-09-22, Last modification date: 2023-11-15)
Primary citation	Xu, Z.,Cetin, B.,Anger, M.,Cho, U.S.,Helmhart, W.,Nasmyth, K.,Xu, W. Structure and function of the PP2A-shugoshin interaction Mol.Cell, 35:426-441, 2009 Cited by PubMed: 19716788 DOI: 10.1016/j.molcel.2009.06.031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation