4IIS

Crystal structure of a glycosylated beta-1,3-glucanase (HEV B 2), An allergen from Hevea Brasiliensis (Space group P41)

Replaces:  3F55

Summary for 4IIS

• Entry DOI: 10.2210/pdb4iis/pdb
• Related: 4HPG
• Descriptor: Beta-1,3-glucanase form 'RRII Gln 2', 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, ... (6 entities in total)
• Functional Keywords: allergen, glycoprotein, glycoside hydrolase, gh17 family, pathogenesis-related class-2 protein, tim-barrel, glycosidase, carbohydrate/sugar binding, piroglutamate (n-terminal residue), latex, hydrolase
• Biological source: Hevea brasiliensis (Para rubber tree,jebe,rubbertree,siringa)
• Total number of polymer chains: 4
• Total formula weight: 142427.87

Authors

Rodriguez-Romero, A.,Hernandez-Santoyo, A. (deposition date: 2012-12-20, release date: 2013-11-27, Last modification date: 2023-09-20)

• Primary citation: Rodriguez-Romero, A.,Hernandez-Santoyo, A.,Fuentes-Silva, D.,Palomares, L.A.,Munoz-Cruz, S.,Yepez-Mulia, L.,Orozco-Martinez, S.; Structural analysis of the endogenous glycoallergen Hev b 2 (endo-beta-1,3-glucanase) from Hevea brasiliensis and its recognition by human basophils.; Acta Crystallogr.,Sect.D, 70:329-341, 2014; PubMed: 24531467; DOI: 10.1107/S1399004713027673

Experimental method

X-RAY DIFFRACTION (2.6676 Å)