3F48

Crystal structure of LeuT bound to L-alanine and sodium

Summary for 3F48

Entry DOI	10.2210/pdb3f48/pdb
Related	2A65 2QEI 3F3A 3F3C 3F3D 3F3E 3F4I 3F4J
Descriptor	Transporter, octyl beta-D-glucopyranoside, SODIUM ION, ... (5 entities in total)
Functional Keywords	membrane protein, nss, slc6, occluded, substrate, sodium-coupled, neurotransmitter, transporter, symport, transmembrane, transport, transport protein
Biological source	Aquifex aeolicus
Total number of polymer chains	1
Total formula weight	59966.73
Authors	Singh, S.K.,Piscitelli, C.L.,Yamashita, A.,Gouaux, E. (deposition date: 2008-10-31, release date: 2008-12-23, Last modification date: 2023-09-06)
Primary citation	Singh, S.K.,Piscitelli, C.L.,Yamashita, A.,Gouaux, E. A competitive inhibitor traps LeuT in an open-to-out conformation. Science, 322:1655-1661, 2008 Cited by PubMed: 19074341 DOI: 10.1126/science.1166777 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation